Key benefits of the single-use bioprocessing disposable bag

In this day and
age, there is an increasing demand for biologics, and now there are many
companies in the biotech industry using what is known as single-use bioprocessing
disposable bag technologies to facilitate quick
turnaround of products.
Single-use systems
(SUS) are biopharmaceutical or bioprocessing manufacturing equipment that are designed
to be used only once and then thrown away. In general, SUS equipment is made up
of primarily plastic components that have been sealed and sterilized with the
help of gamma irradiation. In this article, we will discuss the reasons why
companies love to use this product and its benefits.
Highly Cost-effective
This single-use
bioprocessing disposable equipment can really help in cost savings. It has
helped to eliminate the complex process of sterilization and cleaning of the bioreactor
systems and accessories. Now one can simply just use it and dispose of it when
it is at the end of its lifespan. Therefore, the single-use bioprocessing
systems play a crucial role in helping to reduce the heavy investments needed
in the biotech industry.
Highly Productive
In addition, the
use of the single-use bioprocessing system has helped to increase the overall
productivity of the manufacturing processes due to reduction in complexity of
the need for sterilization and cleaning as mentioned. It has helped to reduce direct
cost in labour and materials as well. The cost of labour needed to assemble the
SUS is much lower compared to the creation of the stainless steel hardware
systems. The use of the single-use systems also removes the need for additional
sterilize-in-place (SIP) steps, which reduces the overall operating costs.
Easy Disposal
The significant
difference as one may easily notice is that these single-use operations is that
they are highly disposable and do not require intense inspection and
sanitation. In addition, the materials used to manufacture these items can be
easily disposed after use, thus cutting down on maintenance.
Less Energy Demand
In actual fact,
using single-use systems compared to conventional equipment has greatly reduced
the need for water use, and thus reduces the overall energy consumption. At
present, it is mentioned that biopharmaceutical manufacturing plants that
transited have experienced almost a 50{ae514a3737d85ea64aeb2cb88bf523835c3e1315e3b3c65ffee7dd6cf13b9d2b} decline in total water consumption
compared to the stainless-steel reactor set-up.
Safety
Lastly, companies
using these single-use systems enjoy a greater safety level. It is a known fact
that product contamination has always been a major problem in the healthcare
industry. Because the same process equipment is used time and time again, this
leads to the production of several antibodies or proteins. Through the use of
the single-use systems, the risk of contamination is greatly reduced as a new
sanitized batch is always used after.

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